9NYM
Crystal structure of an MKP5 allosteric loop mutant, N448A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dual specificity protein phosphatase 10 | polymer | 148 | 17023.6 | 2 | UniProt (Q9Y6W6) Pfam (PF00782) | Homo sapiens (human) | Mitogen-activated protein kinase phosphatase 5,MAP kinase phosphatase 5,MKP-5 |
| 2 | C, D (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A, B: 320 - 466 (UniProt: Q9Y6W6)
| PDB | External Database | Details |
|---|---|---|
| Met 319 | - | initiating methionine |
| Ala 448 | Asn 448 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34047.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 34239.2 |
