9NTY
Crystal structure of calcium-dependent protein kinase 1 (CDPK1) from Cryptosporidium parvum in complex with inhibitor BKI-1708.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calmodulin-domain protein kinase 1 | polymer | 492 | 56710.4 | 1 | UniProt (A3FQ16) | Cryptosporidium parvum Iowa II | |
| 2 | B (A) | (3M)-5-amino-3-[6-(cyclopropyloxy)naphthalen-2-yl]-1-(3-hydroxy-2,2-dimethylpropyl)-1H-pyrazole-4-carboxamide | non-polymer | 394.5 | 1 | Chemie (A1B1T) | |||
| 3 | C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) PubChem (271) | |||
| 4 | F (A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 70 - 538 (UniProt: A3FQ16)
| PDB | External Database | Details |
|---|---|---|
| Met 47 | - | initiating methionine |
| Gly 48 | - | expression tag |
| Ser 49 | - | expression tag |
| Ser 50 | - | expression tag |
| His 51 | - | expression tag |
| His 52 | - | expression tag |
| His 53 | - | expression tag |
| His 54 | - | expression tag |
| His 55 | - | expression tag |
| His 56 | - | expression tag |
| Ser 57 | - | expression tag |
| Ser 58 | - | expression tag |
| Gly 59 | - | expression tag |
| Arg 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Asn 62 | - | expression tag |
| Leu 63 | - | expression tag |
| Tyr 64 | - | expression tag |
| Phe 65 | - | expression tag |
| Gln 66 | - | expression tag |
| Gly 67 | - | expression tag |
| His 68 | - | expression tag |
| Met 69 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56710.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 514.7 | |
| All* | Total formula weight | 57225.1 |
