9NTJ

Chimeric Adenosine deaminase growth factor (ADGF) in complex with pentostatin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Adenosine deaminase AGSA,Adenosine deaminase AGSA,AMP deaminase	polymer	536	61383.2	2	UniProt (P15287) Pfam (PF08451) Pfam (PF00962)	Aplysia californica (California sea hare)	Atrial gland-specific antigen,AGSA,Mollusk-derived growth factor,MDGF
2	C (C)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G22573RC)
3	D, E, F, L, M... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)
4	G, H, I, P, Q... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	J, S (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
6	K, T (A, B)	2'-DEOXYCOFORMYCIN	non-polymer		268.3	2	Chemie (DCF)
7	U, V (A, B)	water	water		18.0	79	Chemie (HOH)

Sequence modifications

A, B: 1 - 120 (UniProt: P15287)
A, B: 121 - 254 (PDB: 9NTJ)
A, B: 255 - 526 (UniProt: P15287)

PDB	External Database	Details
His 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122766.4
Branched	Number of molecules	1
	Total formula weight	748.7
Non-Polymers*	Number of molecules	17
	Total formula weight	2588.2
All*	Total formula weight	126103.3

*Water molecules are not included.