9NTD

Cryo-EM structure of UL5/UL8/UL52 from Herpes Simplex Virus 1 in the presence of ATP-gamma-S

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UL5	polymer	882	98842.3	1	UniProt (A0A2U9A5B2)	Human alphaherpesvirus 1 (Herpes simplex virus type 1)
2	B (B)	UL52	polymer	1058	114592.5	1	UniProt (A0A2U9A692)	Human alphaherpesvirus 1 (Herpes simplex virus type 1)
3	C (C)	UL8	polymer	768	82218.1	1	UniProt (A0A5J6DVE7)	Human alphaherpesvirus 1 (Herpes simplex virus type 1)
4	D (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN) PubChem (32051)

Sequence modifications

A: 42 - 882 (UniProt: A0A2U9A5B2)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 2	-	expression tag
Ala 3	-	expression tag
Ala 4	-	expression tag
Gly 5	-	expression tag
Gly 6	-	expression tag
Glu 7	-	expression tag
Arg 8	-	expression tag
Gln 9	-	expression tag
Leu 10	-	expression tag
Asp 11	-	expression tag
Gly 12	-	expression tag
Gln 13	-	expression tag
Lys 14	-	expression tag
Pro 15	-	expression tag
Gly 16	-	expression tag
Pro 17	-	expression tag
Pro 18	-	expression tag
His 19	-	expression tag
Leu 20	-	expression tag
Gln 21	-	expression tag
Gln 22	-	expression tag
Pro 23	-	expression tag
Gly 24	-	expression tag
Asp 25	-	expression tag
Arg 26	-	expression tag
Pro 27	-	expression tag
Ala 28	-	expression tag
Val 29	-	expression tag
Pro 30	-	expression tag
Gly 31	-	expression tag
Arg 32	-	expression tag
Ala 33	-	expression tag
Glu 34	-	expression tag
Ala 35	-	expression tag
Phe 36	-	expression tag
Leu 37	-	expression tag
Asn 38	-	expression tag
Phe 39	-	expression tag
Thr 40	-	expression tag
Ser 41	-	expression tag
Leu 205	Ser 164	conflict
Val 690	Gly 649	conflict

B: 1 - 1058 (UniProt: A0A2U9A692)

PDB	External Database	Details
Glu 129	Asp 129	conflict
Val 166	Ile 166	conflict
Ser 385	Asn 385	conflict
Asp 514	Gly 514	conflict
Gln 530	Arg 530	conflict
Pro 703	Ser 703	conflict
Ala 719	Thr 719	conflict

C: 1 - 750 (UniProt: A0A5J6DVE7)

PDB	External Database	Details
Met -17	-	initiating methionine
Arg -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Gly -7	-	expression tag
Met -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Asp 467	Asn 467	conflict
Asn 565	Ser 565	conflict
Gly 612	Cys 612	conflict
Val 634	Leu 634	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	295652.9
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	295718.3

*Water molecules are not included.