9NRU
Crystal structure of the H5 influenza virus hemagglutinin from A/duck/France/161108h/2016 (H5N8) clade 2.3.4.4b in complex with O-linked glycan 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 chain | polymer | 329 | 37149.1 | 3 | UniProt (A0A6M2RJB8) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 chain | polymer | 181 | 20851.1 | 3 | UniProt (A0A6M2RJB8) | Influenza A virus | |
| 3 | G, H, I, J (l, G, H, I) | peptide linker | polymer | 5 | 535.6 | 4 | Homo sapiens | ||
| 4 | K (J) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | ||||
| 5 | L (K) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | ||||
| 6 | M (L) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | ||||
| 7 | N, O (M, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | ||||
| 8 | P (O) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | ||||
| 9 | Q, R, S, T (P, Q, R, S) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(3-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 877.8 | 4 | ||||
| 10 | GA, HA, QA, U, V... (C, E, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) PubChem (24139) | |||
| 11 | IA, RA, X (C, E, A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 12 | AA, BA, CA, DA, EA... (A, B, C, E, F) | SULFATE ION | non-polymer | 96.1 | 23 | Chemie (SO4) | |||
| 13 | AB, BB, CB, DB, EB... (A, B, C, D, E...) | water | water | 18.0 | 1090 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: A0A6M2RJB8)
B, D, F: 1 - 174 (UniProt: A0A6M2RJB8)
| PDB | External Database | Details |
|---|---|---|
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 175 | - | expression tag |
| Gly 176 | - | expression tag |
| Arg 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Val 179 | - | expression tag |
| Pro 180 | - | expression tag |
| Arg 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 176143.0 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 7809.1 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 3813.0 | |
| All* | Total formula weight | 187765.1 |
