9NRT
Crystal structure of the H5 influenza virus hemagglutinin from A/duck/France/161108h/2016 (H5N8) clade 2.3.4.4b in complex with O-linked glycan 25
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 chain | polymer | 329 | 37149.1 | 3 | UniProt (A0A6M2RJB8) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 chain | polymer | 181 | 20851.1 | 3 | UniProt (A0A6M2RJB8) | Influenza A virus | |
| 3 | G, H, I, J (G, H, I, J) | Peptide linker | polymer | 5 | 535.6 | 4 | Homo sapiens | ||
| 4 | K (K) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 5 | L (L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 6 | M, O (M, O) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G11971MR) | |||
| 7 | N (N) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | P (P) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | Q (Q) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G18638YB) | |||
| 10 | R (l) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 877.8 | 1 | In PDB GlyTouCan (G64844ET) | |||
| 11 | S, T, U, V (R, S, T, U) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G00035MO) | |||
| 12 | AA, BA, EB, GB, HB... (A, D, E, B, C...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 26 | Chemie (EDO) | |||
| 13 | AB, BB, CA, CB, DA... (C, A, E) | SULFATE ION | non-polymer | 96.1 | 26 | Chemie (SO4) | |||
| 14 | FB, OA (E, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 15 | AC, BC, CC, DC, EC... (C, D, E, F, G...) | water | water | 18.0 | 1791 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: A0A6M2RJB8)
B, D, F: 1 - 174 (UniProt: A0A6M2RJB8)
| PDB | External Database | Details |
|---|---|---|
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 175 | - | expression tag |
| Gly 176 | - | expression tag |
| Arg 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Val 179 | - | expression tag |
| Pro 180 | - | expression tag |
| Arg 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 176143.0 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 7265.8 | |
| Non-Polymers* | Number of molecules | 54 |
| Total formula weight | 4553.8 | |
| All* | Total formula weight | 187962.6 |
