9NRL

Cryo-EM structure of UL52 catalytic core in complex with UL8 subunit from Herpes Simplex Virus 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UL8	polymer	768	82218.1	1	UniProt (A0A5J6DVE7)	Human alphaherpesvirus 1 (Herpes simplex virus type 1)
2	B (B)	UL52	polymer	1058	114592.5	1	UniProt (A0A2U9A692)	Human alphaherpesvirus 1 (Herpes simplex virus type 1)

Sequence modifications

A: 1 - 750 (UniProt: A0A5J6DVE7)

PDB	External Database	Details
Met -17	-	initiating methionine
Arg -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Gly -7	-	expression tag
Met -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Asp 467	Asn 467	conflict
Asn 565	Ser 565	conflict
Gly 612	Cys 612	conflict
Val 634	Leu 634	conflict

B: 1 - 1058 (UniProt: A0A2U9A692)

PDB	External Database	Details
Glu 129	Asp 129	conflict
Val 166	Ile 166	conflict
Ser 385	Asn 385	conflict
Asp 514	Gly 514	conflict
Gln 530	Arg 530	conflict
Pro 703	Ser 703	conflict
Ala 719	Thr 719	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	196810.6
All*	Total formula weight	196810.6

*Water molecules are not included.