9NRG

CCT G beta 5 R269E complex state 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (N)	Guanine nucleotide-binding protein subunit beta-5	polymer	441	48307.2	1	UniProt (O14775)	Homo sapiens (human)	Gbeta5,Transducin beta chain 5
2	B, J (A, a)	T-complex protein 1 subunit alpha	polymer	556	60418.5	2	UniProt (P17987)	Homo sapiens (human)	TCP-1-alpha,CCT-alpha
3	C, K (B, b)	T-complex protein 1 subunit beta	polymer	535	57567.1	2	UniProt (P78371)	Homo sapiens (human)	TCP-1-beta,CCT-beta
4	D, L (D, d)	T-complex protein 1 subunit delta	polymer	539	57996.1	2	UniProt (P50991)	Homo sapiens (human)	TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding
5	E, M (E, e)	T-complex protein 1 subunit epsilon	polymer	541	59750.0	2	UniProt (P48643)	Homo sapiens (human)	TCP-1-epsilon,CCT-epsilon
6	F, N (G, g)	T-complex protein 1 subunit gamma	polymer	545	60613.9	2	UniProt (P49368)	Homo sapiens (human)	TCP-1-gamma,CCT-gamma,hTRiC5
7	G, O (H, h)	T-complex protein 1 subunit eta	polymer	543	59443.5	2	UniProt (Q99832)	Homo sapiens (human)	TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein
8	H, P (Q, q)	T-complex protein 1 subunit theta	polymer	548	59691.4	2	UniProt (P50990)	Homo sapiens (human)	TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15
9	I, Q (Z, z)	T-complex protein 1 subunit zeta	polymer	531	58106.1	2	UniProt (P40227)	Homo sapiens (human)	TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20
10	AA, BB, DA, EB, GA... (E, g, G, h, H...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	16	Chemie (ADP)
11	BA, CB, EA, FB, HA... (E, g, G, h, H...)	MAGNESIUM ION	non-polymer		24.3	16	Chemie (MG) PubChem (888)
12	AB, CA, DB, FA, GB... (e, E, g, G, h...)	ALUMINUM FLUORIDE	non-polymer		84.0	16	Chemie (AF3) PubChem (2124)
13	AC, BC, CC, NB, OB... (h, q, z, A, B...)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

N: 249 - 395 (UniProt: O14775)

PDB	External Database	Details
Met 217	-	initiating methionine
Trp 218	-	expression tag
Ser 219	-	expression tag
His 220	-	expression tag
Pro 221	-	expression tag
Gln 222	-	expression tag
Phe 223	-	expression tag
Glu 224	-	expression tag
Lys 225	-	expression tag
Gly 226	-	expression tag
Gly 227	-	expression tag
Gly 228	-	expression tag
Ser 229	-	expression tag
Gly 230	-	expression tag
Gly 231	-	expression tag
Gly 232	-	expression tag
Ser 233	-	expression tag
Gly 234	-	expression tag
Gly 235	-	expression tag
Ser 236	-	expression tag
Ser 237	-	expression tag
Ala 238	-	expression tag
Trp 239	-	expression tag
Ser 240	-	expression tag
His 241	-	expression tag
Pro 242	-	expression tag
Gln 243	-	expression tag
Phe 244	-	expression tag
Glu 245	-	expression tag
Lys 246	-	expression tag
Ala 247	-	expression tag
Ala 248	-	expression tag
Glu 269	Arg 269	engineered mutation
Gly 396	-	expression tag
Gly 397	-	expression tag
Glu 398	-	expression tag
Asp 399	-	expression tag
Gln 400	-	expression tag
Val 401	-	expression tag
Asp 402	-	expression tag
Pro 403	-	expression tag
Arg 404	-	expression tag
Leu 405	-	expression tag
Ile 406	-	expression tag
Asp 407	-	expression tag
Gly 408	-	expression tag
Lys 409	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	17
	Total formula weight	995480.4
Non-Polymers*	Number of molecules	48
	Total formula weight	8567.7
All*	Total formula weight	1004048.1

*Water molecules are not included.