9NR5

Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/black swan/Akita/1/2016 with LSTc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin HA1	polymer	324	36509.5	3	UniProt (A0A1L7N0F8) Pfam (PF00509)	Influenza A virus
2	B, D, F (B, D, F)	Hemagglutinin HA2	polymer	177	20442.5	3	UniProt (A0A1L7N0F8) Pfam (PF00509)	Influenza A virus
3	G, H, J (G, H, J)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	I (I)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	K, L, M (K, L, M)	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	3	In PDB BIRD (PRD_900046) GlyTouCan (G73578JC)
6	N, O, P, Q, R... (A, C, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
7	T, U, V, W, X... (A, B, C, D, E...)	water	water		18.0	56	Chemie (HOH)

Sequence modifications

A, C, E: 11 - 326 (UniProt: A0A1L7N0F8)

PDB	External Database	Details
Pro 9	-	expression tag
Gly 10	-	expression tag
Leu 226	Gln 237	engineered mutation

B, D, F: 1 - 174 (UniProt: A0A1L7N0F8)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	170855.9
Branched	Number of molecules	7
	Total formula weight	3883.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	176066.7

*Water molecules are not included.