9NQZ
cryo-EM structure of broad betacoronavirus binding antibody 1871 in complex with OC43 S2 subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 585 | 64176.9 | 3 | UniProt (A0A0B4N716) Pfam (PF01601) | Human coronavirus OC43 | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, I (D, F, L) | 1871 Fab light chain | polymer | 109 | 12022.5 | 3 | Homo sapiens | ||
| 3 | E, G, H (E, G, H) | 1871 Fab heavy chain | polymer | 125 | 13589.2 | 3 | Homo sapiens |
Sequence modifications
A, B, C: 2 - 534 (UniProt: A0A0B4N716)
| PDB | External Database | Details |
|---|---|---|
| - | Leu 1289 | deletion |
| Gly 535 | - | expression tag |
| Ser 536 | - | expression tag |
| Glu 537 | - | expression tag |
| Asn 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Tyr 540 | - | expression tag |
| Phe 541 | - | expression tag |
| Gln 542 | - | expression tag |
| Ser 543 | - | expression tag |
| Gly 544 | - | expression tag |
| Ser 545 | - | expression tag |
| Gly 546 | - | expression tag |
| Gly 547 | - | expression tag |
| Gly 548 | - | expression tag |
| Gly 549 | - | expression tag |
| Ser 550 | - | expression tag |
| Gly 551 | - | expression tag |
| Tyr 552 | - | expression tag |
| Ile 553 | - | expression tag |
| Pro 554 | - | expression tag |
| Glu 555 | - | expression tag |
| Ala 556 | - | expression tag |
| Pro 557 | - | expression tag |
| Arg 558 | - | expression tag |
| Asp 559 | - | expression tag |
| Gly 560 | - | expression tag |
| Gln 561 | - | expression tag |
| Ala 562 | - | expression tag |
| Tyr 563 | - | expression tag |
| Val 564 | - | expression tag |
| Arg 565 | - | expression tag |
| Lys 566 | - | expression tag |
| Asp 567 | - | expression tag |
| Gly 568 | - | expression tag |
| Glu 569 | - | expression tag |
| Trp 570 | - | expression tag |
| Val 571 | - | expression tag |
| Leu 572 | - | expression tag |
| Leu 573 | - | expression tag |
| Ser 574 | - | expression tag |
| Thr 575 | - | expression tag |
| Phe 576 | - | expression tag |
| Leu 577 | - | expression tag |
| Gly 578 | - | expression tag |
| His 579 | - | expression tag |
| His 580 | - | expression tag |
| His 581 | - | expression tag |
| His 582 | - | expression tag |
| His 583 | - | expression tag |
| His 584 | - | expression tag |
| His 585 | - | expression tag |
| His 586 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 269366.0 | |
| All* | Total formula weight | 269366.0 |
