9NPH
X-ray crystal structure of recombinant Can f 1 in complex with human IgE mAb 1J11 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1J11 Fab light chain | polymer | 212 | 22717.0 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | 1J11 Fab heavy chain | polymer | 235 | 25320.5 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Major allergen Can f 1 | polymer | 149 | 16569.7 | 1 | UniProt (O18873) | Canis lupus familiaris (dog) | Allergen Dog 1 |
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, L (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 6 | F, G, H, I, J... (A, B, C) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 7 | T, U, V (A, B, C) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
C: 9 - 156 (UniProt: O18873)
| PDB | External Database | Details |
|---|---|---|
| Gly 8 | - | expression tag |
| Ser 100 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 64607.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1946.6 | |
| All* | Total formula weight | 66553.9 |
