9NPG
X-ray crystal structure of recombinant Can f 1-C100S in complex with human IgE mAb 12F3 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, I (A, D, G, K) | IgE 12F3 Fab heavy chain | polymer | 231 | 24638.5 | 4 | Homo sapiens (human) | ||
| 2 | B, E, H, J (B, E, H, J) | IgE 12F3 Fab light chain | polymer | 215 | 23393.0 | 4 | Homo sapiens (human) | ||
| 3 | C, F, K, L (C, F, L, I) | Major allergen Can f 1 | polymer | 148 | 16512.6 | 4 | UniProt (O18873) Pfam (PF00061) | Canis lupus familiaris (dog) | Allergen Dog 1 |
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
C, F, L, I: 9 - 156 (UniProt: O18873)
| PDB | External Database | Details |
|---|---|---|
| Ser 100 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 258176.7 | |
| All* | Total formula weight | 258176.7 |
