9NOW
Human sweet taste receptor (TAS1R2 + TAS1R3) VFT domains bound to aspartame
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Taste receptor type 1 member 3 | polymer | 528 | 58379.6 | 1 | UniProt (Q7RTX0) Pfam (PF01094) Pfam (PF07562) | Homo sapiens (human) | Sweet taste receptor T1R3 |
| 2 | B (A) | Taste receptor type 1 member 2 | polymer | 527 | 60070.5 | 1 | UniProt (Q8TE23) Pfam (PF01094) Pfam (PF07562) | Homo sapiens (human) | G-protein coupled receptor 71,Sweet taste receptor T1R2 |
| 3 | C, D, E, F, G... (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
B: 21 - 521 (UniProt: Q7RTX0)
A: 19 - 518 (UniProt: Q8TE23)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| Lys -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Ile -3 | - | expression tag |
| Ile -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Tyr 2 | - | expression tag |
| Ile 3 | - | expression tag |
| Phe 4 | - | expression tag |
| Cys 5 | - | expression tag |
| Leu 6 | - | expression tag |
| Val 7 | - | expression tag |
| Phe 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Asp 10 | - | expression tag |
| Tyr 11 | - | expression tag |
| Lys 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Asp 15 | - | expression tag |
| Asp 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Ala 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Ala 20 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| Lys -7 | - | expression tag |
| Thr -6 | - | expression tag |
| Ile -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Tyr 0 | - | expression tag |
| Ile 1 | - | expression tag |
| Phe 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Val 5 | - | expression tag |
| Phe 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Tyr 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Tyr 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Val 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Tyr 15 | - | expression tag |
| Ala 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Ala 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118450.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 121768.2 |
