9NOO

CCT G beta 5 S123L complex state 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, I (A, a)	T-complex protein 1 subunit alpha	polymer	556	60418.5	2	UniProt (P17987)	Homo sapiens (human)	TCP-1-alpha,CCT-alpha
2	B, J (B, b)	T-complex protein 1 subunit beta	polymer	535	57567.1	2	UniProt (P78371)	Homo sapiens (human)	TCP-1-beta,CCT-beta
3	C, K (D, d)	T-complex protein 1 subunit delta	polymer	539	57996.1	2	UniProt (P50991)	Homo sapiens (human)	TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding
4	D, L (E, e)	T-complex protein 1 subunit epsilon	polymer	541	59750.0	2	UniProt (P48643)	Homo sapiens (human)	TCP-1-epsilon,CCT-epsilon
5	E, M (G, g)	T-complex protein 1 subunit gamma	polymer	545	60613.9	2	UniProt (P49368)	Homo sapiens (human)	TCP-1-gamma,CCT-gamma,hTRiC5
6	F, N (H, h)	T-complex protein 1 subunit eta	polymer	543	59443.5	2	UniProt (Q99832)	Homo sapiens (human)	TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein
7	G, O (Q, q)	T-complex protein 1 subunit theta	polymer	548	59691.4	2	UniProt (P50990)	Homo sapiens (human)	TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15
8	H, P (Z, z)	T-complex protein 1 subunit zeta	polymer	531	58106.1	2	UniProt (P40227)	Homo sapiens (human)	TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20
9	Q (N)	Guanine nucleotide-binding protein subunit beta-5	polymer	441	48361.4	1	UniProt (O14775)	Homo sapiens (human)	Gbeta5,Transducin beta chain 5
10	AA, BB, DA, EB, GA... (E, g, G, h, H...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	16	Chemie (ADP)
11	BA, CB, EA, FB, HA... (E, g, G, h, H...)	MAGNESIUM ION	non-polymer		24.3	16	Chemie (MG) PubChem (888)
12	AB, CA, DB, FA, GB... (e, E, g, G, h...)	ALUMINUM FLUORIDE	non-polymer		84.0	16	Chemie (AF3) PubChem (2124)
13	AC, BC, CC, NB, OB... (h, q, z, A, B...)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

N: 1 - 395 (UniProt: O14775)

PDB	External Database	Details
Met -31	-	initiating methionine
Trp -30	-	expression tag
Ser -29	-	expression tag
His -28	-	expression tag
Pro -27	-	expression tag
Gln -26	-	expression tag
Phe -25	-	expression tag
Glu -24	-	expression tag
Lys -23	-	expression tag
Gly -22	-	expression tag
Gly -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
Gly -18	-	expression tag
Gly -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Ala -10	-	expression tag
Trp -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
Pro -6	-	expression tag
Gln -5	-	expression tag
Phe -4	-	expression tag
Glu -3	-	expression tag
Lys -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag
Leu 123	Ser 123	engineered mutation
Gly 396	-	expression tag
Gly 397	-	expression tag
Glu 398	-	expression tag
Asp 399	-	expression tag
Gln 400	-	expression tag
Val 401	-	expression tag
Asp 402	-	expression tag
Pro 403	-	expression tag
Arg 404	-	expression tag
Leu 405	-	expression tag
Ile 406	-	expression tag
Asp 407	-	expression tag
Gly 408	-	expression tag
Lys 409	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	17
	Total formula weight	995534.6
Non-Polymers*	Number of molecules	48
	Total formula weight	8567.7
All*	Total formula weight	1004102.3

*Water molecules are not included.