9NNF
Cryo-EM structure of a de-novo designed binder NY1-B04 in complex with HLA-A*02:01 and NY-ESO-1-derived peptide SLLMWITQC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | De-novo designed binder NY1-B04 | polymer | 145 | 15054.3 | 1 | synthetic construct | ||
| 2 | B (B) | HLA class I histocompatibility antigen, A alpha chain | polymer | 276 | 31951.3 | 1 | UniProt (Q861F7) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 4 | D (D) | NY-ESO-1-derived peptide SLLMWITQC | polymer | 9 | 1094.3 | 1 | UniProt (by SIFTS) (P78358) | Escherichia coli |
Sequence modifications
C: 423 - 521 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 422 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59979.3 | |
| All* | Total formula weight | 59979.3 |
