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9NMP

Structure of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(E, F, G, H)
Peptidyl-prolyl cis-trans isomerase FKBP1Apolymer10811939.64UniProt (P26883)
Pfam (PF00254)
Mus musculus (house mouse)PPIase FKBP1A,12 kDa FK506-binding protein,12 kDa FKBP,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase
2E, F, G, H
(D, A, B, C)
Ryanodine receptor 1polymer5035565692.64UniProt (E9PZQ0)
Pfam (PF08709)
Pfam (PF01365)
Pfam (PF02026)
Pfam (PF08454)
Pfam (PF06459)
Pfam (PF00520)
Pfam (PF02815)
Pfam (PF00622)
Pfam (PF21119)
Mus musculus (house mouse)RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor
3AA, I, JA, R
(B, D, C, A)
ZINC IONnon-polymer65.44Chemie (ZN)
4BA, J, KA, S
(B, D, C, A)
CAFFEINEnon-polymer194.24Chemie (CFF)
5CA, GA, K, LA, O...
(B, D, C, A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.28Chemie (ATP)
6DA, L, MA, U
(B, D, C, A)
CALCIUM IONnon-polymer40.14Chemie (CA)
7EA, FA, M, N, NA...
(B, D, C, A)
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer787.18Chemie (PCW)
8HA, IA, P, Q, QA...
(B, D, C, A)
Simvastatinnon-polymer418.68Chemie (A1BYZ)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight2310528.8
Non-Polymers*Number of molecules36
Total formula weight14901.7
All*Total formula weight2325430.4
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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