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9NM0

AZ5104 (metabolite of AZD9291) in complex with WT EGFR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Epidermal growth factor receptorpolymer32737304.11UniProt (P00533)
Pfam (PF07714)
Homo sapiens (human)Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1
2B
(A)
N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamidenon-polymer485.61Chemie (VO7)
3C
(A)
waterwater18.043Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37304.1
Non-Polymers*Number of molecules1
Total formula weight485.6
All*Total formula weight37789.7
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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