9NJS
human polycystin-2 with clinical variant D511V
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (a, b, c, d) | Polycystin-2 | polymer | 745 | 85433.9 | 4 | UniProt (Q13563) | Homo sapiens (human) | PC2,Autosomal dominant polycystic kidney disease type II protein,Polycystic kidney disease 2 protein,Polycystwin,R48321,Transient receptor potential cation channel subfamily P member 2 |
| 2 | E, F, G, H, I... (a, b, c, d) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) PubChem (24139) |
Sequence modifications
a, b, c, d: 53 - 792 (UniProt: Q13563)
| PDB | External Database | Details |
|---|---|---|
| Gly 48 | - | expression tag |
| Ala 49 | - | expression tag |
| Met 50 | - | expression tag |
| Gly 51 | - | expression tag |
| Ser 52 | - | expression tag |
| Val 511 | Asp 511 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 341735.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 344390.1 |
