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9NJO

Y100F Mutant of E. coli Dihydrofolate Reductase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate reductasepolymer15918003.31UniProt (P0ABQ4)
Pfam (PF00186)
Escherichia coli
2B, C, D, E
(A)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
3F
(A)
waterwater18.0171Chemie (HOH)
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
PDBExternal DatabaseDetails
Phe 100Tyr 100engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18003.3
Non-Polymers*Number of molecules4
Total formula weight219.8
All*Total formula weight18223.1
*Water molecules are not included.

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PDB entries from 2026-03-25

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