9NJL
MARV GP in complex with MARV16 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (H, I, J) | MARV16 Heavy Chain | polymer | 223 | 23921.7 | 3 | Mus musculus (mouse) | ||
| 2 | B, F, J (L, N, P) | MARV16 Light Chain | polymer | 214 | 23236.8 | 3 | Mus musculus (mouse) | ||
| 3 | C, G, K (A, C, E) | Envelope glycoprotein GP1 | polymer | 266 | 29689.8 | 3 | UniProt (P35253) Pfam (PF01611) | Orthomarburgvirus marburgense | GP1,2,GP,Virion spike glycoprotein |
| 4 | D, H, L (B, D, F) | Envelope glycoprotein GP2 | polymer | 211 | 23433.0 | 3 | UniProt (P35253) Pfam (PF22307) | Orthomarburgvirus marburgense | |
| 5 | M, O, Q (G, M, Q) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | N, P, R (K, O, R) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 7 | AA, S, T, U, V... (E, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 8 | BA, CA, DA, EA, FA... (H, L, A, B, I...) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 256 (UniProt: P35253)
B, D, F: 436 - 637 (UniProt: P35253)
| PDB | External Database | Details |
|---|---|---|
| Gln 257 | - | expression tag |
| His 258 | - | expression tag |
| Leu 259 | - | expression tag |
| Val 260 | - | expression tag |
| Tyr 261 | - | expression tag |
| Phe 262 | - | expression tag |
| Arg 263 | - | expression tag |
| Arg 264 | - | expression tag |
| Lys 265 | - | expression tag |
| Arg 266 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 439 | Trp 439 | engineered mutation |
| Gly 445 | Phe 445 | engineered mutation |
| Asn 447 | Phe 447 | engineered mutation |
| Ile 589 | His 589 | engineered mutation |
| Ser 638 | - | expression tag |
| His 639 | - | expression tag |
| His 640 | - | expression tag |
| His 641 | - | expression tag |
| His 642 | - | expression tag |
| His 643 | - | expression tag |
| His 644 | - | expression tag |
| His 645 | - | expression tag |
| His 646 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 300844.1 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4978.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 307813.5 |
