9NFR
Crystal structure of CRBN-DDB1 and MRT-23227 in complex with VAV1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA damage-binding protein 1 | polymer | 1140 | 127097.5 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 2 | B (B) | Protein cereblon | polymer | 442 | 50603.7 | 1 | UniProt (Q96SW2) Pfam (PF02190) Pfam (PF03226) | Homo sapiens (human) | |
| 3 | C (C) | Proto-oncogene vav | polymer | 59 | 6913.8 | 1 | UniProt (P15498) Pfam (PF00018) | Homo sapiens (human) | |
| 4 | D (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (B) | (3R)-3-{2-chloro-4'-[(1-methyl-1H-pyrazol-3-yl)methoxy][1,1'-biphenyl]-3-yl}piperidine-2,6-dione | non-polymer | 409.9 | 1 | Chemie (A1BYX) |
Sequence modifications
C: 782 - 839 (UniProt: P15498)
| PDB | External Database | Details |
|---|---|---|
| Gly 781 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 184615.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 475.3 | |
| All* | Total formula weight | 185090.2 |
