9NE9
Human polymerase epsilon bound to PCNA and DNA with a pre-existing mismatch in the blocked conformation I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase epsilon catalytic subunit A | polymer | 1172 | 135390.7 | 1 | UniProt (Q07864) Pfam (PF03104) Pfam (PF22634) | Homo sapiens (human) | 3'-5' exodeoxyribonuclease,DNA polymerase II subunit A |
| 2 | B, C, D (B, C, D) | Proliferating cell nuclear antigen | polymer | 261 | 28795.8 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (human) | PCNA,Cyclin |
| 3 | E (P) | DNA (35-MER) | polymer | 32 | 9908.4 | 1 | synthetic construct | ||
| 4 | F (T) | DNA (49-MER) | polymer | 33 | 10115.6 | 1 | synthetic construct | ||
| 5 | G, H (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | I (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 241801.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 400.3 | |
| All* | Total formula weight | 242202.2 |
