9NDU
Crystal Structure of Ferric Human ADO C18S/C239S Variant in Complex with Hydralazine at 1.98 Angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-aminoethanethiol dioxygenase | polymer | 270 | 29754.7 | 2 | UniProt (Q96SZ5) Pfam (PF07847) | Homo sapiens (human) | Cysteamine dioxygenase |
| 2 | C, I (A, B) | FE (III) ION | non-polymer | 55.8 | 2 | Chemie (FE) | |||
| 3 | D, H, J, K (A, B) | 1-hydrazinophthalazine | non-polymer | 160.2 | 4 | Chemie (HLZ) | |||
| 4 | E, G, L (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 270 (UniProt: Q96SZ5)
| PDB | External Database | Details |
|---|---|---|
| Ser 18 | Cys 18 | engineered mutation |
| Ser 239 | Cys 239 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59509.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1132.7 | |
| All* | Total formula weight | 60642.1 |
