9NCZ
Crystal structure of human AlkBH3 in complex with manganese and 2-oxoglutarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 | polymer | 250 | 29073.6 | 1 | UniProt (Q96Q83) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 3,hABH3,DEPC-1,Prostate cancer antigen 1 |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A: 65 - 286 (UniProt: Q96Q83)
| PDB | External Database | Details |
|---|---|---|
| Met 37 | - | initiating methionine |
| Gly 38 | - | expression tag |
| Ser 39 | - | expression tag |
| Ser 40 | - | expression tag |
| His 41 | - | expression tag |
| His 42 | - | expression tag |
| His 43 | - | expression tag |
| His 44 | - | expression tag |
| His 45 | - | expression tag |
| His 46 | - | expression tag |
| Ser 47 | - | expression tag |
| Ser 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Leu 50 | - | expression tag |
| Val 51 | - | expression tag |
| Pro 52 | - | expression tag |
| Arg 53 | - | expression tag |
| Gly 54 | - | expression tag |
| Thr 55 | - | expression tag |
| Thr 56 | - | expression tag |
| Glu 57 | - | expression tag |
| Asn 58 | - | expression tag |
| Leu 59 | - | expression tag |
| Tyr 60 | - | expression tag |
| Phe 61 | - | expression tag |
| Gln 62 | - | expression tag |
| Gly 63 | - | expression tag |
| Ser 64 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29073.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 236.5 | |
| All* | Total formula weight | 29310.1 |
