9NC8

AMC008 v4.2 SOSIP Env trimer in complex with one 3BC315 Fab

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (E, A, C)	Envelope glycoprotein gp120	polymer	488	55212.5	3		Human immunodeficiency virus 1
2	B, D, F (F, B, D)	Env polyprotein	polymer	154	17428.8	3	UniProt (Q1AII4)	Human immunodeficiency virus 1
3	G (H)	3BC315 Fab heavy chain	polymer	232	24999.2	1		Homo sapiens (human)
4	H (L)	3BC315 Fab light chain	polymer	216	23009.6	1		Homo sapiens (human)
5	I, K, M, P, T (G, J, M, P, T)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	5	In PDB GlyTouCan (G81315DD)
6	J (I)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
7	L, N, O, Q, R... (K, N, O, Q, R...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
8	AA, AB, BA, BB, CA... (E, C, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	36	Chemie (NAG)

Sequence modifications

F, B, D: 512 - 664 (UniProt: Q1AII4)

PDB	External Database	Details
Thr 514	Ala 4	conflict
Asn 543	Gln 33	conflict
Pro 559	Ile 49	conflict
Cys 605	Thr 95	conflict
Ser 607	Ala 97	conflict
Thr 612	Ala 102	conflict
Leu 646	Ile 136	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	265932.9
Branched	Number of molecules	12
	Total formula weight	6876.4
Non-Polymers*	Number of molecules	36
	Total formula weight	7963.5
All*	Total formula weight	280772.7

*Water molecules are not included.