9NC3
AMC008 v4.2 SOSIP Env trimer in complex with b12 and 3BC315 Fabs
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Envelope glycoprotein gp120 | polymer | 488 | 55212.5 | 3 | Human immunodeficiency virus 1 | ||
| 2 | B, D, F (B, D, F) | Envelope glycoprotein gp41 | polymer | 154 | 17412.9 | 3 | UniProt (Q1AII4) | Human immunodeficiency virus 1 | |
| 3 | G, K, O (G, K, O) | 3BC315 Fab heavy chain | polymer | 232 | 24999.2 | 3 | Homo sapiens (human) | ||
| 4 | H, L, P (H, L, P) | 3BC315 Fab light chain | polymer | 216 | 23009.6 | 3 | Homo sapiens (human) | ||
| 5 | I, M, Q (I, M, Q) | b12 Fab heavy chain | polymer | 230 | 24910.8 | 3 | Homo sapiens (human) | ||
| 6 | J, N, R (J, N, R) | b12 Fab light chain | polymer | 215 | 23707.4 | 3 | Homo sapiens (human) | ||
| 7 | AA, CA, EA, GA, IA... (a, c, e, g, i...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 12 | In PDB GlyTouCan (G42666HT) | |||
| 8 | U (U) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 9 | Y (Y) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 10 | DA, JA, QA, Z (d, j, q, Z) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 4 | In PDB GlyTouCan (G15407YE) | |||
| 11 | BA (b) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G61846BY) | |||
| 12 | FA, NA, OA (f, n, o) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 13 | HA, PA (h, p) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
| 14 | KA (k) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 15 | AB, BB, CB, DB, EB... (C, E, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 22 | Chemie (NAG) |
Sequence modifications
B, D, F: 511 - 664 (UniProt: Q1AII4)
| PDB | External Database | Details |
|---|---|---|
| Thr 514 | Ala 4 | conflict |
| Asn 543 | Gln 33 | conflict |
| Pro 559 | Ile 49 | conflict |
| Cys 605 | Thr 95 | conflict |
| Ser 607 | Ala 97 | conflict |
| Thr 612 | Ala 102 | conflict |
| Leu 646 | Ile 136 | conflict |
| Leu 659 | Glu 149 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 507757.3 | |
| Branched | Number of molecules | 25 |
| Total formula weight | 15134.0 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 4866.6 | |
| All* | Total formula weight | 527757.8 |
