9NBT
AMC008 v4.2 SOSIP Env trimer in complex with VRC01 and 35O22 Fabs
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, K, Q (A, J, Q) | Envelope glycoprotein gp120 | polymer | 488 | 55212.5 | 3 | Human immunodeficiency virus 1 | ||
| 2 | B, L, R (B, K, R) | Envelope glycoprotein gp41 | polymer | 154 | 17428.8 | 3 | UniProt (Q1AII4) | Homo sapiens (human) | |
| 3 | C, G, M (C, E, M) | VRC01 Fab heavy chain | polymer | 224 | 24395.7 | 3 | Homo sapiens (human) | ||
| 4 | D, H, N (D, F, N) | VRC01 Fab light chain | polymer | 210 | 23172.7 | 3 | Homo sapiens (human) | ||
| 5 | E, I, O (H, G, O) | 35O22 Fab heavy chain | polymer | 243 | 26170.5 | 3 | Homo sapiens (human) | ||
| 6 | F, J, P (L, I, P) | 35O22 Fab light chain | polymer | 216 | 23318.8 | 3 | Homo sapiens (human) | ||
| 7 | FA, KA, S, SA, X... (f, k, S, s, X...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 6 | In PDB GlyTouCan (G22768VO) | |||
| 8 | AA, AB, BA, BB, CA... (a, 0, b, 1, c...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 27 | In PDB GlyTouCan (G42666HT) | |||
| 9 | IA, V, VA (i, V, v) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 10 | LA, Y, YA (l, Y, y) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G94106MV) | |||
| 11 | AC, BC, CC, FB, GB... (Q, A, D, F, J...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
B, K, R: 511 - 664 (UniProt: Q1AII4)
| PDB | External Database | Details |
|---|---|---|
| Thr 514 | Ala 4 | conflict |
| Asn 543 | Gln 33 | conflict |
| Pro 559 | Ile 49 | conflict |
| Cys 605 | Thr 95 | conflict |
| Ser 607 | Ala 97 | conflict |
| Thr 612 | Ala 102 | conflict |
| Leu 646 | Ile 136 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 509097.2 | |
| Branched | Number of molecules | 39 |
| Total formula weight | 21902.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5309.0 | |
| All* | Total formula weight | 536308.5 |
