9NB8
Cryo-EM structure of the CD163/HpSPHb complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Scavenger receptor cysteine-rich type 1 protein M130 | polymer | 1004 | 108626.4 | 3 | UniProt (Q86VB7) Pfam (PF00530) | Homo sapiens (human) | Hemoglobin scavenger receptor |
| 2 | D (D) | Hemoglobin subunit alpha | polymer | 142 | 15281.5 | 1 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | Alpha-globin,Hemoglobin alpha chain |
| 3 | E (E) | Hemoglobin subunit beta | polymer | 147 | 16021.4 | 1 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | Beta-globin,Hemoglobin beta chain |
| 4 | F (F) | Haptoglobin | polymer | 266 | 29690.8 | 1 | UniProt (P00738) Pfam (PF00089) | Homo sapiens (human) | Zonulin |
| 5 | AA, G, H, I, J... (C, A, B) | CALCIUM ION | non-polymer | 40.1 | 21 | Chemie (CA) | |||
| 6 | BA, DA (D, E) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 7 | CA, EA (D, E) | OXYGEN MOLECULE | non-polymer | 32.0 | 2 | Chemie (OXY) |
Sequence modifications
F: 88 - 347 (UniProt: P00738)
| PDB | External Database | Details |
|---|---|---|
| His 82 | - | expression tag |
| His 83 | - | expression tag |
| His 84 | - | expression tag |
| His 85 | - | expression tag |
| His 86 | - | expression tag |
| His 87 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 386872.8 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2138.6 | |
| All* | Total formula weight | 389011.4 |
