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9NA6

IRAK4 in Complex with Compound 34

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Interleukin-1 receptor-associated kinase 4polymer30434215.54UniProt (Q9NWZ3)
Pfam (PF07714)
Homo sapiens (human)IRAK-4,Renal carcinoma antigen NY-REN-64
2E, G, J, L
(A, B, C, D)
(6P)-4-{[(1S)-1-cyanoethyl]amino}-6-[(8S)-3-cyanopyrrolo[1,2-b]pyridazin-7-yl]-N-[(2S)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamidenon-polymer435.54Chemie (A1BWZ)
3F, H, I, K, M...
(A, B, C, D)
SULFATE IONnon-polymer96.17Chemie (SO4)
4P, Q, R, S
(A, B, C, D)
waterwater18.0484Chemie (HOH)
Sequence modifications
A, B, C, D: 160 - 460 (UniProt: Q9NWZ3)
PDBExternal DatabaseDetails
Gly 157-expression tag
Ala 158-expression tag
Met 159-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight136862.1
Non-Polymers*Number of molecules11
Total formula weight2414.3
All*Total formula weight139276.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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