Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-1 receptor-associated kinase 4 | polymer | 304 | 34215.5 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | E, H, L, O (A, B, C, D) | (6P)-6-[(8R)-3-cyanopyrrolo[1,2-b]pyridazin-7-yl]-4-({(1s,4S)-4-[1-(difluoromethyl)-1H-pyrazol-4-yl]cyclohexyl}amino)-N-[(2S)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamide | non-polymer | 580.6 | 4 | Chemie (A1BWY) | |||
| 3 | F, G, I, J, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 4 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 872 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 160 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Gly 157 | - | expression tag |
| Ala 158 | - | expression tag |
| Met 159 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136862.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3379.1 | |
| All* | Total formula weight | 140241.2 |
