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9NA2

IRAK4 in Complex with Compound 9

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Interleukin-1 receptor-associated kinase 4polymer30434215.52UniProt (Q9NWZ3)
Pfam (PF07714)
Homo sapiens (human)IRAK-4,Renal carcinoma antigen NY-REN-64
2C, E
(A, B)
(6P)-6-[(8R)-3-cyanopyrrolo[1,2-b]pyridazin-7-yl]-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-4-(methylamino)pyridine-3-carboxamidenon-polymer396.42Chemie (A1BW0)
3D
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
4F, G
(A, B)
waterwater18.0174Chemie (HOH)
Sequence modifications
A, B: 160 - 460 (UniProt: Q9NWZ3)
PDBExternal DatabaseDetails
Gly 157-expression tag
Ala 158-expression tag
Met 159-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68431.0
Non-Polymers*Number of molecules3
Total formula weight871.0
All*Total formula weight69302.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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