9N9L

An RORgt Inverse agonist for treatment of Psoriasis

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nuclear receptor ROR-gamma	polymer	243	28307.8	2	UniProt (P51449) Pfam (PF00104)	Homo sapiens (human)	Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma
2	C, D (A, B)	(5P)-5-[2,3-dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2-hydroxy-2-methylpropyl)-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide	non-polymer		622.4	2	Chemie (A1BW2) PubChem (121303142) PubChem (121303144) PubChem (121303394)
3	E, F (A, B)	water	water		18.0	156	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56615.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1244.8
All*	Total formula weight	57860.5

*Water molecules are not included.