9N9F
Cryo-EM structure of the SAH domain of human INCENP bound to the paclitaxel-stabilized microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (Q2XVP4) | Sus scrofa (pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
| 2 | B (B) | Tubulin beta chain | polymer | 445 | 49907.8 | 1 | UniProt (P02554) | Sus scrofa (pig) | Beta-tubulin |
| 3 | D (S) | Inner centromere protein | polymer | 941 | 108394.5 | 1 | UniProt (Q9NQS7) | Homo sapiens (human) | |
| 4 | E, K (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | F, M (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G, I, L (B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | H (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 8 | J (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) | |||
| 9 | N, O (B, C) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
S: 1 - 918 (UniProt: Q9NQS7)
| PDB | External Database | Details |
|---|---|---|
| Asp 644 | Glu 644 | variant |
| Pro 919 | - | expression tag |
| Ser 920 | - | expression tag |
| Arg 921 | - | expression tag |
| Leu 922 | - | expression tag |
| Glu 923 | - | expression tag |
| Glu 924 | - | expression tag |
| Glu 925 | - | expression tag |
| Leu 926 | - | expression tag |
| Arg 927 | - | expression tag |
| Arg 928 | - | expression tag |
| Arg 929 | - | expression tag |
| Leu 930 | - | expression tag |
| Thr 931 | - | expression tag |
| Glu 932 | - | expression tag |
| Ser 933 | - | expression tag |
| Asn 934 | - | expression tag |
| Ser 935 | - | expression tag |
| Leu 936 | - | expression tag |
| Glu 937 | - | expression tag |
| Val 938 | - | expression tag |
| Leu 939 | - | expression tag |
| Phe 940 | - | expression tag |
| Gln 941 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258711.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2547.2 | |
| All* | Total formula weight | 261258.3 |
