Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, E) | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 402 | 46329.3 | 2 | UniProt (O75460) Pfam (PF00069) Pfam (PF06479) | Homo sapiens (human) | Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a |
| 2 | B, D (B, F) | von Hippel-Lindau disease tumor suppressor | polymer | 147 | 17031.4 | 2 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (human) | Protein G7,pVHL |
| 3 | E, F (G, C) | Elongin-C | polymer | 94 | 10625.2 | 2 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 4 | G, H (D, H) | Elongin-B peptide | polymer | 6 | 639.7 | 2 | UniProt (Q15370) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 5 | I, J (B, F) | 3-methyl-N-(5-{4-[(1r,4S)-4-{[7-oxo-8-(propan-2-yl)-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}cyclohexyl]piperazin-1-yl}pentanoyl)-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide | non-polymer | 883.2 | 2 | Chemie (A1BWF) | |||
| 6 | K, L, M, N (A, B, E, F) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 149251.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1766.3 | |
| All* | Total formula weight | 151017.5 |
