9N7D

Structure of the Rattus norvegicus ACE2 receptor bound HsItaly2011 RBD complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Angiotensin-converting enzyme 2	polymer	767	88709.8	1	UniProt (Q5EGZ1) Pfam (PF01401) Pfam (PF16959)	Rattus norvegicus (Norway rat)	ACE-related carboxypeptidase
2	B (B)	Spike glycoprotein	polymer	271	29871.7	1	UniProt (A0A2I6PIW5) Pfam (PF09408) UniProt (by SIFTS) (A3EXD0)	Merbecovirus	S glycoprotein,E2,Peplomer protein
3	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
4	G, H, I, K, L (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
5	J (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	M, N (A, B)	water	water		18.0	110	Chemie (HOH)

Sequence modifications

A: 1 - 743 (UniProt: Q5EGZ1)

PDB	External Database	Details
Gly 742	Trp 742	conflict
Asn 744	-	expression tag
Asp 745	-	expression tag
Ile 746	-	expression tag
Phe 747	-	expression tag
Glu 748	-	expression tag
Ala 749	-	expression tag
Gln 750	-	expression tag
Lys 751	-	expression tag
Ile 752	-	expression tag
Glu 753	-	expression tag
Trp 754	-	expression tag
His 755	-	expression tag
Glu 756	-	expression tag
Gly 757	-	expression tag
Gly 758	-	expression tag
Ser 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag
His 762	-	expression tag
His 763	-	expression tag
His 764	-	expression tag
His 765	-	expression tag
His 766	-	expression tag
His 767	-	expression tag

B: 388 - 589 (UniProt: A0A2I6PIW5)

PDB	External Database	Details
Met 356	-	expression tag
Gly 357	-	expression tag
Ile 358	-	expression tag
Leu 359	-	expression tag
Pro 360	-	expression tag
Ser 361	-	expression tag
Pro 362	-	expression tag
Gly 363	-	expression tag
Met 364	-	expression tag
Pro 365	-	expression tag
Ala 366	-	expression tag
Leu 367	-	expression tag
Leu 368	-	expression tag
Ser 369	-	expression tag
Leu 370	-	expression tag
Val 371	-	expression tag
Ser 372	-	expression tag
Leu 373	-	expression tag
Leu 374	-	expression tag
Ser 375	-	expression tag
Val 376	-	expression tag
Leu 377	-	expression tag
Leu 378	-	expression tag
Met 379	-	expression tag
Gly 380	-	expression tag
Cys 381	-	expression tag
Val 382	-	expression tag
Ala 383	-	expression tag
Glu 384	-	expression tag
Thr 385	-	expression tag
Gly 386	-	expression tag
Thr 387	-	expression tag
Leu 590	-	expression tag
Val 591	-	expression tag
Pro 592	-	expression tag
Arg 593	-	expression tag
Gly 594	-	expression tag
Ser 595	-	expression tag
Ser 596	-	expression tag
Ser 597	-	expression tag
Gly 598	-	expression tag
Gly 599	-	expression tag
Ser 600	-	expression tag
Gly 601	-	expression tag
Leu 602	-	expression tag
Asn 603	-	expression tag
Asp 604	-	expression tag
Ile 605	-	expression tag
Phe 606	-	expression tag
Glu 607	-	expression tag
Ala 608	-	expression tag
Gln 609	-	expression tag
Lys 610	-	expression tag
Ile 611	-	expression tag
Glu 612	-	expression tag
Trp 613	-	expression tag
His 614	-	expression tag
Glu 615	-	expression tag
Gly 616	-	expression tag
Gly 617	-	expression tag
Ser 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag
His 625	-	expression tag
His 626	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	118581.4
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1171.4
All*	Total formula weight	121450.5

*Water molecules are not included.