9N4R
Composite map for GluK2-0xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor ionotropic, kainate 2 | polymer | 908 | 102510.0 | 4 | UniProt (P42260) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluK2,Glutamate receptor 6,GluR-6,GluR6 |
| 2 | E, G, I, K (E, G, I, K) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 4 | In PDB GlyTouCan (G22768VO) | |||
| 3 | F, J (F, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | H, L (H, L) | beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G31886NL) | |||
| 5 | BA, JA, M, VA (B, C, A, D) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 4 | Chemie (KAI) | |||
| 6 | CA, DA, KA, LA, MA... (B, C, A, D) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 16 | Chemie (POV) | |||
| 7 | AB, BB, CB, DB, EA... (D, B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 20 | Chemie (NAG) | |||
| 8 | AA, IA, UA, Z (B, D, A) | 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide | non-polymer | 242.3 | 4 | Chemie (2J9) |
Sequence modifications
A, B, C, D: 1 - 908 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Val 567 | Ile 567 | conflict |
| Cys 571 | Tyr 571 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 410039.9 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 5989.5 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 18407.4 | |
| All* | Total formula weight | 434436.7 |
