9N39
DNA gyrase complexed with uncleaved DNA and Compound 185 to 2.25 A resolution
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA gyrase subunit B fusion with DNA gyrase subunit A | polymer | 693 | 78166.1 | 2 | UniProt (P0A0K8) UniProt (P20831) Pfam (PF01751) Pfam (PF00986) Pfam (PF00521) | Staphylococcus aureus | |
| 2 | C, D (C, D) | DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3') | polymer | 20 | 6136.0 | 2 | Escherichia coli | ||
| 3 | E, F (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 4 | G (D) | N-{(2r,5r)-2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-yl}-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide | non-polymer | 463.5 | 1 | Chemie (A1BVQ) | |||
| 5 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A, B: 410 - 1001 (UniProt: P0A0K8)
A, B: 1002 - 1491 (UniProt: P20831)
| PDB | External Database | Details |
|---|---|---|
| Gly 408 | - | expression tag |
| Met 409 | - | expression tag |
| - | Leu 544 | deletion |
| - | Tyr 545 | deletion |
| - | Lys 546 | deletion |
| - | Leu 547 | deletion |
| - | Thr 548 | deletion |
| - | Gln 549 | deletion |
| - | Gly 550 | deletion |
| - | Lys 551 | deletion |
| - | Gln 552 | deletion |
| - | Lys 553 | deletion |
| - | Tyr 554 | deletion |
| - | Tyr 555 | deletion |
| - | Val 556 | deletion |
| - | Tyr 557 | deletion |
| - | Asn 558 | deletion |
| - | Asp 559 | deletion |
| - | Arg 560 | deletion |
| - | Glu 561 | deletion |
| - | Leu 562 | deletion |
| - | Asp 563 | deletion |
| - | Lys 564 | deletion |
| - | Leu 565 | deletion |
| - | Lys 566 | deletion |
| - | Ser 567 | deletion |
| - | Glu 568 | deletion |
| - | Leu 569 | deletion |
| - | Asn 570 | deletion |
| - | Pro 571 | deletion |
| - | Thr 572 | deletion |
| - | Pro 573 | deletion |
| - | Lys 574 | deletion |
| - | Trp 575 | deletion |
| - | Ser 576 | deletion |
| - | Ile 577 | deletion |
| Thr 544 | Ala 578 | conflict |
| Gly 545 | Arg 579 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Phe 1123 | Tyr 123 | conflict |
| Thr 1457 | Ala 457 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 168604.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 573.4 | |
| All* | Total formula weight | 169177.4 |
