9N27

Crystal structure of Melanotaenia fluviatilis estrogen receptor alpha ligand binding domain complexed with Bisphenol TMC

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Estrogen receptor	polymer	251	28714.9	2	UniProt (D6N7U3)	Melanotaenia fluviatilis (Murray River rainbowfish)	ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1
2	C, D, G, H (A, B)	(2~5~S)-2~3~,2~3~,2~5~-trimethyl-2~3~,2~4~,2~5~,2~6~-tetrahydro-2~2~H-[1~1~,2~1~:2~1~,3~1~-terphenyl]-1~4~,3~4~-diol	non-polymer		310.4	4	Chemie (A1BVK)
3	E, F, I, J (A, B)	(2~5~R)-2~3~,2~3~,2~5~-trimethyl-2~3~,2~4~,2~5~,2~6~-tetrahydro-2~2~H-[1~1~,2~1~:2~1~,3~1~-terphenyl]-1~4~,3~4~-diol	non-polymer		310.4	4	Chemie (A1BWR)
4	K, L (A, B)	water	water		18.0	33	Chemie (HOH)

Sequence modifications

A, B: 310 - 553 (UniProt: D6N7U3)

PDB	External Database	Details
Met 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57429.7
Non-Polymers*	Number of molecules	8
	Total formula weight	2483.4
All*	Total formula weight	59913.2

*Water molecules are not included.