9N23
Crystal structure of cIAP1-BIR3 with XB2 series SMAC mimetic ligand
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Baculoviral IAP repeat-containing protein 2 | polymer | 95 | 11020.4 | 2 | UniProt (Q13490) Pfam (PF00653) | Homo sapiens (human) | Cellular inhibitor of apoptosis 1,C-IAP1,IAP homolog B,Inhibitor of apoptosis protein 2,hIAP-2,hIAP2,RING finger protein 48,RING-type E3 ubiquitin transferase BIRC2,TNFR2-TRAF-signaling complex protein 2 |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | N-methyl-L-alanyl-3-methyl-L-valyl-N-(2-fluoro-5-methoxyphenyl)-L-prolinamide | non-polymer | 436.5 | 2 | Chemie (A1BVC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B: 254 - 346 (UniProt: Q13490)
| PDB | External Database | Details |
|---|---|---|
| Gly 252 | - | expression tag |
| Ser 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22040.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1003.9 | |
| All* | Total formula weight | 23044.7 |
