9N21
Crystal structure of XIAP-BIR3 with ALP1 series SMAC mimetic ligand
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase XIAP | polymer | 110 | 12689.1 | 1 | UniProt (P98170) Pfam (PF00653) | Homo sapiens (human) | Baculoviral IAP repeat-containing protein 4,IAP-like protein,ILP,hILP,Inhibitor of apoptosis protein 3,IAP-3,hIAP-3,hIAP3,RING-type E3 ubiquitin transferase XIAP,X-linked inhibitor of apoptosis protein,X-linked IAP |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | N~2~-methyl-N-{6-[(1,3-thiazol-5-yl)ethynyl]pyridin-2-yl}-L-alaninamide | non-polymer | 286.4 | 1 | Chemie (A1BVB) | |||
| 4 | D (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 246 - 354 (UniProt: P98170)
| PDB | External Database | Details |
|---|---|---|
| Gly 245 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12689.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 351.8 | |
| All* | Total formula weight | 13040.9 |
