9MZS
cryoEM structure of GluK2 bound to BPAM344 and glutamate in the non-active state, composite map
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor ionotropic, kainate 2 | polymer | 908 | 102547.0 | 4 | UniProt (P42260) | Rattus norvegicus (Norway rat) | GluK2,Glutamate receptor 6,GluR-6,GluR6 |
| 2 | E, F, H, I, N... (E, F, H, I, N...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 3 | G, J, M (G, J, M) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | K (K) | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G44266EX) | |||
| 5 | L (L) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G53081KU) | |||
| 6 | P, R, U (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 7 | Q, T, W, Z (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 8 | S, V, X, Y (B, C, D) | 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide | non-polymer | 242.3 | 4 | Chemie (2J9) PubChem (67531324) |
Sequence modifications
A, B, C, D: 1 - 908 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Cys 676 | Lys 676 | conflict |
| Cys 802 | Asn 802 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 410188.1 | |
| Branched | Number of molecules | 11 |
| Total formula weight | 5965.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2221.2 | |
| All* | Total formula weight | 418374.9 |
