9MZH

Cryo-EM structure of the Nipah virus polymerase containing the connecting domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (B, C, D, E, G)	Phosphoprotein	polymer	759	84026.4	5	UniProt (Q9IK91)	Henipavirus nipahense	Protein P
2	F, G (H, A)	RNA-directed RNA polymerase L	polymer	2270	260638.6	2	UniProt (Q997F0)	Henipavirus nipahense	Protein L,Large structural protein,Replicase,Transcriptase

Sequence modifications

B, C, D, E, G: 1 - 709 (UniProt: Q9IK91)

PDB	External Database	Details
Met -49	-	initiating methionine
Lys -48	-	expression tag
Ser -47	-	expression tag
Ser -46	-	expression tag
Trp -45	-	expression tag
Ser -44	-	expression tag
His -43	-	expression tag
Pro -42	-	expression tag
Gln -41	-	expression tag
Phe -40	-	expression tag
Glu -39	-	expression tag
Lys -38	-	expression tag
Gly -37	-	expression tag
Ala -36	-	expression tag
Met -35	-	expression tag
Thr -34	-	expression tag
Gly -33	-	expression tag
Trp -32	-	expression tag
Ser -31	-	expression tag
His -30	-	expression tag
Pro -29	-	expression tag
Gln -28	-	expression tag
Phe -27	-	expression tag
Glu -26	-	expression tag
Lys -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Ala -21	-	expression tag
Ser -20	-	expression tag
Trp -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
Pro -16	-	expression tag
Gln -15	-	expression tag
Phe -14	-	expression tag
Glu -13	-	expression tag
Lys -12	-	expression tag
Gly -11	-	expression tag
Ala -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Ser -3	-	expression tag
Asn -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

H, A: 1 - 2244 (UniProt: Q997F0)

PDB	External Database	Details
Met -25	-	expression tag
Lys -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	941409.3
All*	Total formula weight	941409.3

*Water molecules are not included.