9MX9
Crystal structure of the DNA binding domain of FLI1 (F362A) in complex with a DNA containing two contiguous GGAA sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Friend leukemia integration 1 transcription factor | polymer | 145 | 16710.8 | 2 | UniProt (Q01543) Pfam (PF00178) | Homo sapiens (human) | Proto-oncogene Fli-1,Transcription factor ERGB |
| 2 | C (E) | DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3') | polymer | 15 | 4708.1 | 1 | synthetic construct | ||
| 3 | D (F) | DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3') | polymer | 15 | 4471.9 | 1 | synthetic construct | ||
| 4 | E, F, G, H, I (A, D, E, F) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 5 | J, K (A, D) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, D: 259 - 399 (UniProt: Q01543)
| PDB | External Database | Details |
|---|---|---|
| Gly 255 | - | expression tag |
| Pro 256 | - | expression tag |
| His 257 | - | expression tag |
| Met 258 | - | expression tag |
| Ala 362 | Phe 362 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42601.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 200.4 | |
| All* | Total formula weight | 42801.9 |
