9MVU
C6 Herpes Virus Simplex Neutralizing Nanobody Bound to HSV Glycoprotein gB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Envelope glycoprotein B | polymer | 727 | 82038.0 | 3 | UniProt (P10211) Pfam (PF17416) Pfam (PF17417) Pfam (PF00606) UniProt (by SIFTS) (P08666) | Human herpesvirus 1 (strain 17) (HHV-1 Human herpes simplex virus 1) | gB |
| 2 | D, E, F (D, E, F) | C6 Neutralizing Nanobody | polymer | 131 | 14339.8 | 3 | Homo sapiens (human) | ||
| 3 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 4362 | Chemie (HOH) |
Sequence modifications
A, B, C: 28 - 730 (UniProt: P10211)
| PDB | External Database | Details |
|---|---|---|
| Pro 29 | Ser 29 | conflict |
| Ala 33 | Ser 33 | conflict |
| Ala 34 | Ser 34 | conflict |
| Arg 36 | Gly 36 | conflict |
| Ala 37 | Thr 37 | conflict |
| Ser 38 | Pro 38 | conflict |
| Gly 40 | Val 40 | conflict |
| Val 41 | Ala 41 | conflict |
| Val 45 | Gln 45 | conflict |
| Ser 53 | Thr 53 | conflict |
| Arg 54 | Pro 54 | conflict |
| Pro 55 | Ala 55 | conflict |
| Val 58 | Ala 58 | conflict |
| Ser 60 | Gly 60 | conflict |
| Pro 61 | Ala 61 | conflict |
| Ala 62 | Pro 62 | conflict |
| Thr 63 | Pro 63 | conflict |
| Lys 65 | Gly 65 | conflict |
| Ala 66 | Asp 66 | conflict |
| Arg 67 | Pro 67 | conflict |
| Arg 69 | Pro 69 | conflict |
| Thr 71 | Lys 71 | conflict |
| Lys 72 | Asn 72 | conflict |
| Lys 73 | Arg 73 | variant |
| Pro 74 | Lys 74 | conflict |
| Arg 77 | Pro 77 | conflict |
| Glu 79 | Lys 79 | conflict |
| Ala 80 | Pro 80 | conflict |
| Thr 81 | Pro 81 | conflict |
| Pro 82 | Arg 82 | conflict |
| Pro 84 | Ala 84 | conflict |
| Asp 85 | Gly 85 | conflict |
| Ala 86 | Asp 86 | conflict |
| Ala 99 | Glu 99 | conflict |
| Glu 103 | Asp 103 | conflict |
| Val 106 | Ala 106 | conflict |
| Ala 109 | Thr 109 | conflict |
| Met 218 | Leu 218 | conflict |
| Lys 238 | Asn 238 | conflict |
| Val 239 | Ala 239 | conflict |
| Ser 338 | Ala 338 | conflict |
| Ala 362 | Ser 362 | conflict |
| Ala 378 | Ser 378 | conflict |
| Ser 403 | Pro 403 | conflict |
| Arg 415 | Lys 415 | conflict |
| Glu 419 | Asp 419 | conflict |
| Ile 421 | Met 421 | conflict |
| Met 424 | Ile 424 | conflict |
| Lys 428 | Arg 428 | conflict |
| Thr 445 | Asn 445 | conflict |
| Tyr 459 | His 468 | conflict |
| Met 459 | Leu 469 | conflict |
| Asp 459 | Ser 473 | conflict |
| Pro 459 | - | insertion |
| Arg 459 | - | insertion |
| Asn 459 | Pro 476 | conflict |
| Ala 459 | Pro 477 | conflict |
| Thr 459 | Asn 478 | conflict |
| Ala 459 | Thr 480 | conflict |
| Leu 459 | Pro 482 | conflict |
| Arg 459 | Pro 483 | conflict |
| Glu 460 | Pro 484 | conflict |
| Ala 460 | Gly 485 | conflict |
| Pro 460 | Ala 486 | conflict |
| Ile 524 | Val 524 | conflict |
| Val 526 | Ile 526 | conflict |
| Pro 578 | Ala 578 | conflict |
| Val 589 | Ile 589 | conflict |
| Thr 595 | Ala 595 | conflict |
| Ile 613 | Val 613 | conflict |
| Leu 630 | Ile 630 | conflict |
| Ile 642 | Thr 642 | conflict |
| Val 664 | Ile 664 | conflict |
| Arg 724 | His 724 | conflict |
| Gly 731 | - | expression tag |
| Gly 732 | - | expression tag |
| Gly 733 | - | expression tag |
| Ser 734 | - | expression tag |
| His 735 | - | expression tag |
| His 736 | - | expression tag |
| His 737 | - | expression tag |
| His 738 | - | expression tag |
| His 739 | - | expression tag |
| His 740 | - | expression tag |
| His 741 | - | expression tag |
| His 742 | - | expression tag |
| Gly 743 | - | expression tag |
| Ser 744 | - | expression tag |
| Asp 745 | - | expression tag |
| Tyr 746 | - | expression tag |
| Lys 747 | - | expression tag |
| Asp 748 | - | expression tag |
| Asp 749 | - | expression tag |
| Asp 750 | - | expression tag |
| Asp 751 | - | expression tag |
| Lys 752 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 289133.6 | |
| All* | Total formula weight | 289133.6 |
