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9MUQ

Crystal structure of unbound N-SH2 domain of SHP2 (1AYD conditions)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 1 of Tyrosine-protein phosphatase non-receptor type 11polymer10912207.61UniProt (Q06124)
Pfam (PF00017)
Homo sapiens (human)Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3
2B
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.035Chemie (HOH)
Sequence modifications
A: 1 - 106 (UniProt: Q06124)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight12207.6
Non-Polymers*Number of molecules2
Total formula weight188.2
All*Total formula weight12395.8
*Water molecules are not included.

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PDB entries from 2026-03-18

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