9MUB
Human IMPDH2 mutant - S160del, treated with GTP, ATP, IMP, and NAD+; tetramer reconstruction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Inosine-5'-monophosphate dehydrogenase 2 | polymer | 518 | 56393.4 | 4 | UniProt (P12268) Pfam (PF00478) Pfam (PF00571) | Homo sapiens (human) | IMP dehydrogenase 2,IMPD 2,IMPDH 2,Inosine-5'-monophosphate dehydrogenase type II,IMP dehydrogenase II,IMPDH-II |
| 2 | E, G, I, K (A, B, C, D) | INOSINIC ACID | non-polymer | 348.2 | 4 | Chemie (IMP) | |||
| 3 | F, H, J, L (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) |
Sequence modifications
A, B, C, D: 1 - 514 (UniProt: P12268)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| - | Ser 160 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 225573.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4046.5 | |
| All* | Total formula weight | 229620.2 |
