9MT2
Structure of the Machupo virus glycoprotein complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, D, G) | Pre-glycoprotein polyprotein GP complex | polymer | 58 | 6351.6 | 3 | UniProt (Q8AZ57) | Mammarenavirus machupoense | Pre-GP-C |
| 2 | B, E, H (B, E, H) | Pre-glycoprotein polyprotein GP complex | polymer | 204 | 23528.8 | 3 | UniProt (Q8AZ57) Pfam (PF00798) | Mammarenavirus machupoense | Pre-GP-C |
| 3 | C, F, I (C, F, I) | Pre-glycoprotein polyprotein GP complex | polymer | 234 | 27117.4 | 3 | UniProt (Q8AZ57) Pfam (PF00798) | Mammarenavirus machupoense | Pre-GP-C |
| 4 | J, K, L, N, P... (V, T, S, K, M...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 5 | M, O, Q (J, L, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | AA, BA, EA, FA, GA... (F, H, I, B, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 7 | CA, DA, IA, JA, W... (F, I, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) |
Sequence modifications
A, D, G: 1 - 58 (UniProt: Q8AZ57)
B, E, H: 59 - 251 (UniProt: Q8AZ57)
C, F, I: 263 - 496 (UniProt: Q8AZ57)
| PDB | External Database | Details |
|---|---|---|
| Ala 33 | Lys 33 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Lys 252 | - | expression tag |
| Thr 253 | - | expression tag |
| His 254 | - | expression tag |
| Leu 255 | - | expression tag |
| Asn 256 | - | expression tag |
| Phe 257 | - | expression tag |
| Glu 258 | - | expression tag |
| Arg 259 | - | expression tag |
| Ser 260 | - | expression tag |
| Leu 261 | - | expression tag |
| Lys 262 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 333 | Ser 333 | conflict |
| Ala 343 | Thr 343 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 170993.4 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4792.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3047.0 | |
| All* | Total formula weight | 178832.8 |
