9MSX

Candida albicans Hsp90 nucleotide binding domain in complex with TAS116

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heat shock protein 90 homolog	polymer	232	26350.8	2	UniProt (P46598) Pfam (PF02518)	Candida albicans
2	C, E (A, B)	(4P)-3-ethyl-4-[(4P)-4-[(4M)-4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl]-3-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]benzamide	non-polymer		454.5	2	Chemie (A1BPC)
3	D, F (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	G, H (A, B)	water	water		18.0	92	Chemie (HOH)

Sequence modifications

A, B: 1 - 218 (UniProt: P46598)

PDB	External Database	Details
Asn 219	-	expression tag
Leu 220	-	expression tag
Tyr 221	-	expression tag
Phe 222	-	expression tag
Gln 223	-	expression tag
Ser 224	-	expression tag
Gly 225	-	expression tag
Ser 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52701.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1033.2
All*	Total formula weight	53734.9

*Water molecules are not included.