9MSD
G002-293-0536 Fab in complex with 001428_T278M_L14 SOSIP and RM20A3 Fab
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K (A, G, B) | 001428_T278M_L14 SOSIP gp140 | polymer | 650 | 72345.6 | 3 | UniProt (A1EAH9) Pfam (PF00516) Pfam (PF00517) UniProt (by SIFTS) (A0A0B5KZH3) | Human immunodeficiency virus 1 | |
| 2 | B, G, L (H, I, N) | G002-293-0536 Fab heavy chain | polymer | 224 | 24206.4 | 3 | Homo sapiens | ||
| 3 | C, H, M (L, M, O) | G002-293-0536 Fab light chain | polymer | 210 | 22943.4 | 3 | Homo sapiens | ||
| 4 | D, I, N (D, F, K) | RM20A3 Fab light chain | polymer | 215 | 22827.2 | 3 | Macaca mulatta | ||
| 5 | E, J, O (C, E, J) | RM20A3 Rab heavy chain | polymer | 228 | 24079.1 | 3 | Macaca mulatta | ||
| 6 | P, Q, S, T, V... (P, Q, S, T, V...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 7 | R, U, X (R, U, X) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 8 | AA, BA, CA, DA, EA... (A, G, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) |
Sequence modifications
A, G, B: 30 - 664 (UniProt: A1EAH9)
| PDB | External Database | Details |
|---|---|---|
| Glu 28 | - | expression tag |
| Thr 29 | - | expression tag |
| Met 278 | Thr 284 | engineered mutation |
| Val 304 | Arg 310 | engineered mutation |
| Tyr 319 | Ala 323 | engineered mutation |
| Cys 501 | Ala 503 | engineered mutation |
| Gly 504 | Glu 509 | engineered mutation |
| Ser 504 | Arg 510 | engineered mutation |
| His 504 | Glu 511 | engineered mutation |
| Ser 504 | Lys 512 | engineered mutation |
| Gly 504 | - | insertion |
| Ser 504 | - | insertion |
| Gly 504 | - | insertion |
| Gly 504 | - | insertion |
| Ser 504 | - | insertion |
| Gly 504 | - | insertion |
| Ser 504 | - | insertion |
| Gly 504 | - | insertion |
| Gly 504 | - | insertion |
| His 504 | - | insertion |
| Ala 504 | Arg 513 | engineered mutation |
| Ser 504 | Phe 521 | engineered mutation |
| Pro 559 | Ile 561 | engineered mutation |
| Pro 561 | Ala 563 | engineered mutation |
| Asp 568 | Leu 570 | engineered mutation |
| His 570 | Val 572 | engineered mutation |
| His 585 | Arg 587 | engineered mutation |
| Cys 605 | Thr 607 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 499204.7 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4306.0 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 5972.6 | |
| All* | Total formula weight | 509483.3 |
