9MR7
Genetiocally detoxified pertussis toxin in complex with hu1B7 Fab and hu11E6 Fab
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pertussis toxin subunit 1 | polymer | 235 | 26148.7 | 1 | UniProt (P04977) Pfam (PF02917) | Bordetella pertussis | PTX S1,Islet-activating protein S1,IAP S1,NAD-dependent ADP-ribosyltransferase |
| 2 | B (B) | Pertussis toxin subunit 2 | polymer | 199 | 21913.7 | 1 | UniProt (P04978) Pfam (PF03440) Pfam (PF02918) | Bordetella pertussis | PTX S2,Islet-activating protein S2,IAP S2 |
| 3 | C (C) | Pertussis toxin subunit 3 | polymer | 199 | 21889.9 | 1 | UniProt (P04979) Pfam (PF03440) Pfam (PF02918) | Bordetella pertussis | PTX S3,Islet-activating protein S3,IAP S3 |
| 4 | D, E (D, E) | Pertussis toxin subunit 4 | polymer | 110 | 12072.4 | 2 | UniProt (P0A3R5) Pfam (PF09275) | Bordetella pertussis | PTX S4,Islet-activating protein S4,IAP S4 |
| 5 | F (F) | Pertussis toxin subunit 5 | polymer | 99 | 10951.5 | 1 | UniProt (P04981) Pfam (PF09276) | Bordetella pertussis | PTX S5,Islet-activating protein S5,IAP S5 |
| 6 | G (G) | hu1B7 Fab light chain | polymer | 213 | 23137.7 | 1 | Mus musculus | ||
| 7 | H (H) | hu1B7 Fab heavy chain | polymer | 223 | 23868.7 | 1 | Mus musculus | ||
| 8 | I, K (I, K) | hu11E6 Fab light chain | polymer | 214 | 23422.0 | 2 | Mus musculus | ||
| 9 | J, L (J, L) | hu11E6 Fab heavy chain | polymer | 228 | 24733.8 | 2 | Mus musculus |
Sequence modifications
A: 1 - 235 (UniProt: P04977)
| PDB | External Database | Details |
|---|---|---|
| Lys 9 | Arg 43 | conflict |
| Gly 129 | Glu 163 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 248366.5 | |
| All* | Total formula weight | 248366.5 |
